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SUMMARY:Jean Cadigan - Ethical Governance of Human Genome Editing | GES Colloquium [ZOOM ONLY]
DESCRIPTION:Colloquium Home | Zoom Registration | GES Colloquium Videos | Colloquium Podcast | LinkedIn | Newsletter | Publications Podcast \nSPRING SEMINAR SERIES\n\n\n\n\n\n\nDue to inclement weather\, our seminar with Dr. Cadigan will now be held over Zoom only and the lunch has been cancelled. Register at https:/go.ncsu.edu/ges-colloq-zoom \n\nGoverning Genome Editing at the Boundaries: Empirical Insights from Human Health Applications\nNow Zoom Only | Drawing on empirical research on human genome editing\, this talk examines how ethical questions around enhancement\, disease seriousness\, and governance are negotiated in practice\, with implications beyond human health. \nThis talk draws on empirical research on human genome editing to examine how ethical boundaries around enhancement\, disease seriousness\, and governance are understood and negotiated in practice. Focusing on how scientists\, clinicians\, and policy professionals make sense of emerging genome‑editing technologies\, the presentation highlights tensions between categorical policy distinctions and the context‑sensitive judgments required under conditions of uncertainty and clinical urgency. Rather than treating ethical boundaries as fixed or purely normative\, the findings illustrate how they are shaped through anticipatory reasoning\, institutional constraints\, and efforts to act responsibly in the face of incomplete knowledge. Although grounded in human health applications\, this analysis offers insights relevant to broader debates about responsible innovation and the governance of genetic engineering across domains. \nRelated links: \n\nIncidental Enhancement: Addressing a Neglected Policy Issue in Human Genome Editing\, NIH National Human Genome Research Institute project\, R.J. Cadigan (PI)\nDownload seminar poster\n\nJean Cadigan\, PhD\nProfessor at University of North Carolina at Chapel Hill | Profile \nJean Cadigan\, PhD\, is a Professor of Social Medicine at the University of North Carolina at Chapel Hill whose work focuses on the ethical\, legal\, and social implications of emerging genomic technologies. A medical anthropologist\, she conducts empirical research on how scientists\, clinicians\, policymakers\, and publics understand and navigate ethical boundaries in areas such as human genome editing and genomic medicine. She recently led an NIH‑funded study\, “Incidental Enhancement: Addressing a Neglected Policy Issue in Human Genome Editing\,” which investigated how concerns about enhancement arise in the context of ostensibly therapeutic genome‑editing interventions. She is delighted to be affiliated with GES through PreMiEr’s Social and Ethical Implications (SEI) research focus. \n\nThe Genetic Engineering and Society (GES) Colloquium is a seminar series that brings in speakers to present and stimulate discussion on a variety of topics related to existing and proposed biotechnologies and their place within broader societal changes. \nGES Colloquium is taught by Dr. Zack Brown\, and the seminars serve as a great opportunity for our students to build their networks and grow as professionals. To support their efforts\, we encourage you to join our in-person seminars\, which will now take place in Nelson 4305. \nRemember\, we regularly post colloquium seminars as videos on Panopto and on our GES Lectures podcast\, allowing you to revisit or catch up on these recordings at your convenience. \nPlease subscribe to the GES newsletter and LinkedIn for updates.
URL:https://ges.research.ncsu.edu/event/colloquium-2026-02-03/
LOCATION:Zoom
CATEGORIES:Colloquium,GES Event
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ORGANIZER;CN="GES Center":MAILTO:gesocietycenter@ncsu.edu
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DTSTART;TZID=America/New_York:20260210T120000
DTEND;TZID=America/New_York:20260210T130000
DTSTAMP:20260506T024720
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SUMMARY:J. Royden Saah - Gene Drive Research Forum: Convening Evidence\, Governance\, and Dialogue Through a One Health Lens | GES Colloquium [Hybrid]
DESCRIPTION:Colloquium Home | Zoom Registration | GES Colloquium Videos | Colloquium Podcast | LinkedIn | Newsletter | Publications Podcast \nSPRING SEMINAR SERIES\nGene Drive Research Forum: Convening Evidence\, Governance\, and Dialogue Through a One Health Lens\nNelson 4305 + Zoom | Learn how GeneConvene’s Gene Drive Research Forum brings together cross-sector expertise and dialogue to strengthen decision-making and responsible governance for gene drive and related genetic biocontrol approaches. \nJoin us for lunch after colloquium\n\n\n\n\n\n\n  \nThis colloquium will introduce GeneConvene’s Gene Drive Research Forum as an interdisciplinary convening platform that strengthens responsible research and decision-making on gene drive and related genetic biocontrol approaches through a One Health lens. The presentation will show how GeneConvene—and the Forum in particular—integrates evidence from the life sciences\, social sciences\, ethics\, and regulatory practice to inform governance and support meaningful dialogue among researchers\, public health practitioners\, environmental stakeholders\, and communities. We will review the Forum’s core activities and share emerging lessons on translating complex evidence into accessible\, context-sensitive insights that can inform policy and practice. \nRelated links: \n\nGeneConvene\nLinkedIn\nDownload seminar poster\n\nMr. J. Royden Saah\, MS\nSenior Technical Expert at GeneConvene/Foundation for the National Institutes of Health | Profile \nJ. Royden Saah is a global health and biosafety leader with more than two decades of experience building pandemic preparedness\, infectious disease response\, and research-to-operations programs in the U.S. and internationally. He currently serves as a Senior Technical Expert at FNIH’s GeneConvene. He came to the foundation after coordinating the Genetic Biocontrol of Invasive Rodents program at Island Conservation\, supporting a multi-institution\, multinational network developing novel biotechnologies for vector and pest management. His prior roles include senior leadership at the North Carolina State Laboratory of Public Health and international outbreak response deployments\, including COVID-19 and the West African Ebola epidemic. He holds a BS in Zoology and an MS in Microbiology\, both from North Carolina State University. \n\nThe Genetic Engineering and Society (GES) Colloquium is a seminar series that brings in speakers to present and stimulate discussion on a variety of topics related to existing and proposed biotechnologies and their place within broader societal changes. \nGES Colloquium is taught by Dr. Zack Brown\, and the seminars serve as a great opportunity for our students to build their networks and grow as professionals. To support their efforts\, we encourage you to join our in-person seminars\, which will now take place in Nelson 4305. \nRemember\, we regularly post colloquium seminars as videos on Panopto and on our GES Lectures podcast\, allowing you to revisit or catch up on these recordings at your convenience. \nPlease subscribe to the GES newsletter and LinkedIn for updates.
URL:https://ges.research.ncsu.edu/event/colloquium-2026-2-10/
LOCATION:4305 Nelson Hall\, 2801 Founders Dr\, Raleigh\, NC\, 27607\, United States
CATEGORIES:Colloquium,GES Event
ATTACH;FMTTYPE=image/jpeg:https://ges.research.ncsu.edu/wp-content/uploads/2025/12/021026_Colloquium_Royden-Saah_web.jpg
ORGANIZER;CN="GES Center":MAILTO:gesocietycenter@ncsu.edu
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DTSTART;TZID=America/New_York:20260224T120000
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SUMMARY:Jake Warner - Genome editing in corals | GES Colloquium [Zoom]
DESCRIPTION:Colloquium Home | Zoom Registration | GES Colloquium Videos | Colloquium Podcast | LinkedIn | Newsletter | Publications Podcast \nSPRING SEMINAR SERIES\nGenome editing in corals\nZoom ONLY | An overview of the state of genome editing technology in corals and the ethical issues they elicit. \nCoral reefs worldwide are experiencing unprecedented losses. Rising sea surface temperatures\, declining seawater pH\, pollutants\, and disease are among the many factors that have led to coral population decline. Given the varied nature of these threats\, it is unlikely that a ‘one size fits all’ approach to conservation and restoration will be sufficient. Precision genomics\, including genome modification and transgenics\, affords new opportunities to develop tailored solutions to these problems. Genomic modification in corals has thus far been hindered by technical difficulties including logistical challenges associated with coral reproduction and the low success rate of traditional transgenic approaches more broadly. Our group has overcome both limitations by successfully spawning corals in captivity year over year\, and by developing a novel\, high- throughput\, gene knock-in strategy which we have demonstrated in several cnidarians including corals. There are potentially transformative applications of this technology: coral transgenic lines could\, eventually\, be used to drive expression of beneficial gene products that confer tolerance to heat\, disease\, or other stressors. At the same time\, with our bioethics collaborators we are examining the potential ethical\, environmental\, and policy implications of deploying this technology in corals to generate a framework to guide future stakeholders in its implementation. \n\nWarner Lab\nDownload seminar poster > \n\nJake Warner\, PhD\nAssociate Professor at UNC Wilmington | Profile \nDr. Warner’s lab seeks to understand early development of Stony corals\, a long overlooked field of developmental biology. He uses a combination of single cell omics\, imaging\, and perturbations to derive the gene regulatory networks of early cell type specification in developing corals. His group recently published the first transgenic ‘knock-in’ coral (Warner et al 2025). His group has garnered significant recognition and is funded by the NSF\, NIH and international organizations \n\nThe Genetic Engineering and Society (GES) Colloquium is a seminar series that brings in speakers to present and stimulate discussion on a variety of topics related to existing and proposed biotechnologies and their place within broader societal changes. \nGES Colloquium is taught by Dr. Zack Brown\, and the seminars serve as a great opportunity for our students to build their networks and grow as professionals. To support their efforts\, we encourage you to join our in-person seminars\, which will now take place in Nelson 4305. \nRemember\, we regularly post colloquium seminars as videos on Panopto and on our GES Lectures podcast\, allowing you to revisit or catch up on these recordings at your convenience. \nPlease subscribe to the GES newsletter and LinkedIn for updates.
URL:https://ges.research.ncsu.edu/event/colloquium-2026-02-24/
LOCATION:Zoom
CATEGORIES:Colloquium,GES Event
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ORGANIZER;CN="GES Center":MAILTO:gesocietycenter@ncsu.edu
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